"Those of us with adrenal disease know the importance of having new treatments that will give us an opportunity to have the best quality of life with improved medical options. Participation in clinical trials can help accelerate the development of new treatments and address our community's unmet medical needs."
  --Lori Engler, Executive Director, NADF

CLINCAL RESEARCH STUDY FOR  ADRENOCORTICAL CANCER (acc)

Corcept Therapeutics is now looking for volunteers to participate in a clinical study of the investigational
study drug, relacorilant, in combination with the immunotherapy drug, Keytruda® (pembrolizumab). See details here: 
https://www.nadf.us/corcept-clinical-trial-for-adrenocortical-cancer-acc.html

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CLINICAL RESEARCH STUDY FOR ENDOGENOUS CUSHING SYNROME

The purpose of the Grace Study is to evaluate the effectiveness (benefits) and safety (side effects) of an investigational study medicine, relacorilant, in treating participants with endogenous Cushing syndrome. See details here: ​https://www.nadf.us/grace-study---endogenous-cushing-syndrome.html

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CLINICAL RESEARCH STUDIES FOR ADULTS AND CHILDREN WITH CONGENITAL ADRENAL HYPERPLASIA (CAH)

If you or your child has congenital adrenal hyperplasia, the CAH Studies may be of interest to you. See more information here: https://www.nadf.us/cahtalyst-study-cah.html​

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​A STUDY OF GENE THERAPY FOR CLASSIC CONGENITAL ADRENAL HYPERPLASIA (CAH)

BridgeBio affiliate, Adrenas Therapeutics, is enrolling adults in a gene therapy trial for classic CAH. See more information here. https://www.nadf.us/gene-therapy-for-classic-cah.html​ 

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SPRUCE BIOSCIENCES NOW ENROLLING CAHMELIA CLINICAL TRIAL

Spruce Biosciences, a late-stage clinical development company focused on developing and commercializing novel therapies for rare endocrine disorders, is now enrolling patients with classic CAH into the CAHmelia clinical trials. See more here. https://www.nadf.us/cahmelia-adult-studies-classic-cah.html​.

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the Spark-PA study for primary aldosteronism

Spark-PA is conducting a clinical research study exploring an investigational therapy (study drug) for people with high blood pressure caused by PA. For more information, visit https://www.nadf.us/primary-aldosteronism-study.html​

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NADF does not endorse any product, merely informing our members about a new clinical trial.