The National Adrenal Diseases Foundation informs, educates, and supports those with adrenal disease and their families to improve their quality of life.

Visit our YouTube page for informative videos. Return monthly for new videos.


Pfizer Canada is recalling 8 lots of Solu-Cortef
(hydrocortisone sodium succinate for injection)
100mg/2mL single-dose Act-O-Vial as a result of a labelling text error on the side panel of the carton which indicates that the reconstituted product contains 125 mg/mL hydrocortisone instead of 50 mg/mL.
This could lead to a potential dosing error.

Products affected:
Solu-Cortef (hydrocortisone sodium succinate for injection) 100 mg/2 mL single-dose Act-O-Vial sterile powder and diluent, DIN 00030600, supplied in packages of 10 vials.


NEW! Diagnosis and Treatment of Primary Adrenal Insufficiency Guideline

This clinical practice guideline addresses the diagnosis and treatment of primary adrenal insufficiency.

Download the guide: An Endocrine Society Clinical Practice Guideline.

NADF joins the Autoimmune Research Network (ARNet)

If you have Addison’s disease caused by autoimmunity, please complete the ARNet survey at This will only take about 15 minutes and could make a huge difference in future research.

NADF is encouraging you to fill out the information as we hope this can lead to a better understanding of Addison’s, including research on its causes, potential treatments, and perhaps even a cure. If NADF learns you might be eligible candidate for a study, we will contact you with information about the research.

NADF joined the Autoimmune Research Network (ARNet) in hopes that it will boost autoimmunity research, including Addison’s disease.
Click here for details.

Clinical trial for adrenal patients has trials that are related to the adrenals. We have listed them on a separate page in our Research section. Go here for the Clinical trial for adrenal patients page.

Flu Vaccinations

Dr. Margulies’ Flu Vaccinations Recommendation

NADF Medical Director Paul Margulies, MD, FACE, FACP recommends that all adrenal insufficient patients (Addison’s disease, secondary adrenal insufficiency, congenital adrenal hyperplasia, adrenomyeloneuropathy, et al.) get their regular yearly flu vaccination.

New Surgery Protocol for Adults

Dr. Paul Margulies’ surgery protocol for Adult Adrenal Insufficient Patients has been updated and you can get this here. Or, visit the Tools for Life page.

The Face of Addison’s Disease

This is an awareness video published by LWA Support Group on YouTube. We need your help to make sure that nobody else dies unnecessarily..
Click here to view this video

American Autoimmune Related Diseases Association (AARDA) Survey

This Affordable Care Act survey was developed by AARDA.
Click here to go to survey


Pfizer, the manufacturer of Solu-Cortef®, in the convenient “acto-vials”, has removed the preservatives from their product, so have been issued a new NDC number by the FDA. The number is 0009001103.

This NDC number change has apparently made it difficult for pharmacies to find the product in their computer systems, with the result of their informing some adrenal insufficient patients that it is no longer available for prescription.

We have created this form [PDF] to inform you and your pharmacy that the product is still available for prescription.

If your pharmacy is having trouble obtaining these products, please instruct them to call Pfizer’s Customer Service at 1(800) 533-4535.

Other possible contact numbers for Pfizer are 1(800) 438-1985 or patient services at 1(888) 691-6813.

Please feel free to make copies of this notice and pass it on to your pharmacy/s. Maybe it will help you avoid the misunderstanding and resulting aggravation some other people have experienced.


Potentially Life-Preserving
Information Packet for Adrenal Insufficient
Patients (including
Addison’s disease)
please download.

click for zip file

click for self-extracting file

(self-extracting file is for PC computers that do not have a zip program.
All you have to do is
double-click on the file
you download to open)


Potentially Life-Preserving
Information Packet for
Congenital Adrenal
Hyperplasia (CAH) Patients
please download.

click for zip file

click for self-extracting file

(self-extracting file is for PC computers that do not have a zip program.
All you have to do is
double-click on the file
you download to open)